Gangrene is caused by a loss of blood supply to the foot or bacterial infections that result from open sores or ulcers. Diabetics are most prone to foot gangrene because they typically have poor circulation or nerve damage, which can lead to loss of blood supply.
Any sudden onset of foot or leg pain accompanied by lower skin temperature and skin color changes may indicate a sudden blockage of blood flow to the legs.
Gangrene is a serious condition, particularly when it is caused by an infection, which can spread throughout the body. Gangrenous tissue must be surgically removed by way of debridement or amputation, followed by oxygen treatment and intravenous antibiotics to kill any infection.