A neuroma is an enlarged, benign growth of nerves, most commonly between the third and fourth toes (specifically called a Morton's neuroma). Neuromas are caused by tissue rubbing against and irritating the nerves. Pressure from poorly fitting shoes, high-heeled or narrow shoes, trauma, or an abnormal bone structure can also lead to this condition. Symptoms may include sensations of thickness, burning, numbness, tingling, or pain in the ball of the foot with pain radiating into the toes. Treatments generally include wearing corrective shoes, padding, orthotics, cortisone injections, or sclerosing alcohol injections. In severe cases, surgical removal of the growth may be necessary.